Annote: A Serious Game for Medical Students to Approach Lesion Skin Images of a Digital Library

Nowadays it is claimed that one method to learn how to execute a task is to present it as a gaming activity: in this way a teacher can offer a safe and controlled environment for learners also arousing excitement and engagement. In this work we present the design of the serious game 'Annote', to exploit a medical digital library with the aim to help dermatologists to teach students how to approach the examination of skin lesion images to prevent melanomas

An Annotation Tool for a Digital Library System of Epidermal Data

Melanoma is one of the deadliest form of skin cancers so it becomes crucial the developing of automated systems that analyze and investigate epidermal images to early identify them also reducing unnecessary medical exams. A key element is the availability of user-friendly annotation tools that can be used by non-IT experts to produce well-annotated and high-quality medical data. In this work, we present an annotation tool to manually crate and annotate digital epidermal images, with the aim to extract meta-data (annotations, contour patterns and intersections, color information) stored and organized in an integrated digital library. This tool is obtained following rigid usability principles also based on doctors interviews and opinions. A preliminary but functional evaluation phase has been conducted with non-medical subjects by using questionnaires, in order to check the general usability and the efficacy of the proposed tool

Affective Classication of Gaming Activities Coming From RPG Gaming Sessions

Each human activity involves feelings and subjective emotions: different people will perform and sense the same task with different outcomes and experience; to understand this experience, concepts like Flow or Boredom must be investigated using objective data provided by methods like electroencephalography. This work carries on the analysis of EEG data coming from brain-computer interface and videogame "Neverwinter Nights 2": we propose an experimental methodology comparing results coming from different off-the-shelf machine learning techniques, employed on the gaming activities, to check if each affective state corresponds to the hypothesis xed in their formal design guidelines

Classification of Affective Data to Evaluate the Level Design in a Role-Playing Videogame

This paper presents a novel approach to evaluate game level design strategies, applied to role playing games. Following a set of well defined guidelines, two game levels were designed for Neverwinter Nights 2 to manipulate particular emotions like boredom or flow, and tested by 13 subjects wearing a brain computer interface helmet. A set of features was extracted from the affective data logs and used to classify different parts of the gaming sessions, to verify the correspondence of the original level aims and the effective results on people emotions. The very interesting correlations observed, suggest that the technique is extensible to other similar evaluation tasks

Affective level design for a role-playing videogame evaluated by a brain\u2013computer interface and machine learning methods

Game science has become a research field, which attracts industry attention due to a worldwide rich sell-market. To understand the player experience, concepts like flow or boredom mental states require formalization and empirical investigation, taking advantage of the objective data that psychophysiological methods like electroencephalography (EEG) can provide. This work studies the affective ludology and shows two different game levels for Neverwinter Nights 2 developed with the aim to manipulate emotions; two sets of affective design guidelines are presented, with a rigorous formalization that considers the characteristics of role-playing genre and its specific gameplay. An empirical investigation with a brain\u2013computer interface headset has been conducted: by extracting numerical data features, machine learning techniques classify the different activities of the gaming sessions (task and events) to verify if their design differentiation coincides with the affective one. The observed results, also supported by subjective questionnaires data, confirm the goodness of the proposed guidelines, suggesting that this evaluation methodology could be extended to other evaluation tasks

Determination of reliable resistance values for electrical double-layer capacitors

The power capabilities of supercapacitors are strongly influenced by their passive elements. Within this study, we investigate methods to address resistive components out of galvanostatic measurements and we compared literature methods with the aim to provide a guide to correctly exploit the resistance of supercapacitors. The impact of the sampling conditions of galvanostatic measurements is analyzed and related to electrochemical impedance spectroscopy. Further, a novel method based on the instantaneous power analysis is provided to get real-time information concerning the actual cell resistance during the measurement without altering the gal- vanostatic experiment. Measurements show that literature methods can provide values close to the series resistance, while the newly proposed power method results in a good estimate of the actual dissipative value

dynamic behaviour of a retrofitted school building subjected to the after shock sequence of the 2016 central italy earthquake

Abstract This paper deals with the dynamic behaviour of a 1960s school building in Camerino subjected to moderate earthquakes belonging to the after-shock sequence of the 2016 Central Italy earthquake. The school structure, constituted by RC frames, was seismically retrofitted by means of "Dissipative Towers", an innovative system based on the use of external stiff steel truss towers equipped with dissipative dampers. Modal properties of the building after the retrofit have been determined through ambient vibration tests. After the main shock of the 2016 Central Italy earthquake, the building was instrumented with low-noise accelerometers and the dynamic behaviour of the structure during several aftershocks was recorded. Firstly, a numerical finite element model of the building is developed and calibrated on the basis of the ambient vibration measurements; then the registered dynamic response of the structure for the highest aftershock event (among the registered ones) is compared with that obtained numerically with the calibrated model. Results demonstrate the good agreement of the registered and predicted response

attentional pattern classification for automatic dementia detection

n/

PhenoCaB : a new phenological model based on carbon balance in boreal conifers

Traditional phenological models use chilling and thermal forcing (temperature sum or degree-days) to predict budbreak. Because of the heightening impact of climate and other related biotic or abiotic stressors, a model with greater biological support is needed to better predict budbreak. Here, we present an original mechanistic model based on the physiological processes taking place before and during budbreak of conifers. As a general principle, we assume that phenology is driven by the carbon status of the plant, which is closely related to environmental variables and the annual cycle of dormancy-activity. The carbon balance of a branch was modelled from autumn to winter with cold acclimation and dormancy and from winter to spring when deacclimation and growth resumption occur. After being calibrated in a field experiment, the model was validated across a large area (> 34 000 km 2 ), covering multiple conifers stands in Québec (Canada) and across heated plots for the SPRUCE experiment in Minnesota (USA). The model accurately predicted the observed dates of budbreak in both Québec (±3.98 d) and Minnesota (±7.98 d). The site-independent calibration provides interesting insights on the physiological mechanisms underlying the dynamics of dormancy break and the resumption of vegetative growth in spring

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London